Publications by authors named "A Voskamp"
Article Synopsis
- B-cells are essential for immune responses, acting as antigen presenters, modulating immunity, and creating immune memory and antibodies.
- The study examined B-cell distributions in people from Indonesia and Ghana, comparing them to those in the Netherlands using advanced mass cytometry.
- Results showed that individuals from rural tropical areas have higher levels of certain memory B-cells and lower naïve B-cells, especially in children, suggesting that greater exposure to microbes enhances the development of memory B-cells which tends to stabilize as they age.
Background: Food allergy is a leading cause of anaphylaxis worldwide. Allergen-specific immunotherapy is the only treatment shown to modify the natural history of allergic disease, but application to food allergy has been hindered by risk of severe allergic reactions and short-lived efficacy. Allergen-derived peptides could provide a solution.
View Article and Find Full Text PDFInnate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. We investigated their role at nasal mucosa following allergen challenge with house dust mite. We combined single-cell proteome and transcriptome profiling on nasal immune cells from nasal biopsies cells from 30 allergic rhinitis and 27 non-allergic subjects before and after repeated nasal allergen challenge.
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