Modulation of Mitochondria-Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis Model.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease without effective treatment. The progressive motoneuron death in ALS is associated with alterations in lipid metabolism. As its regulation occurs in mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs), modulation of mitochondria-ER contacts (MERCs) is emerging as a crucial factor in MAM formation and lipid metabolism control.

Student Violence Against Paraprofessionals in Schools: A Social-Ecological Analysis of Safety and Well-Being.

Violence against teachers has received increasing attention worldwide, with high rates of verbal, threatening, physical, and property violence in schools. Teacher-directed violence contributes to poor mental and physical health, high rates of turnover, and diminished student achievement. Despite these findings, there is a dearth of research on violence experienced by paraprofessionals who play key roles in supporting students with the greatest learning and behavioral needs in schools.

Phytochemistry, Anti-cancer, and Anti-diabetic Properties of Plant-Based Foods from Mexican Agrobiodiversity: A Review.

Type 2 diabetes mellitus (T2DM) and cancer are significant contributors to morbidity and mortality worldwide. Recent studies have increasingly highlighted the potential of phytochemicals found in plants and plant-based foods for preventing and treating these chronic diseases. Mexico's agrobiodiversity provides a valuable resource for phytochemistry.

Evaluation of Antioxidant and Antimicrobial Properties of Murtilla Leaves (.) in Beef Patties: Effects on Quality Parameters and Shelf Life.

Beef patties are highly consumed worldwide. However, its formulations often include synthetic antioxidants and antimicrobials. Murtilla (.