Publications by authors named "A Vestito"
Chemotherapy can cause vascular and metabolic liver injury in patients with liver metastases, but scarce data are available. We aimed to (i) describe the prevalence of porto-sinusoidal vascular disorder (PSVD) among patients undergoing resection for liver metastases; and (ii) assess whether liver (LSM) and spleen stiffness measurements could diagnose PSVD and predict postoperative complications. This is a prospective single-center study enrolling consecutive patients undergoing hepatic resection for metastases at a tertiary center.
View Article and Find Full Text PDFAcute cholecystitis (AC), generally associated with the presence of gallstones, is a relatively frequent disease that can lead to serious complications. For these reasons, AC warrants prompt clinical diagnosis and management. There is general agreement in terms of considering early laparoscopic cholecystectomy (ELC) to be the best treatment for AC.
View Article and Find Full Text PDFAutoimmune atrophic gastritis (AAG) is a chronic condition characterized by the presence of atrophy in the oxyntic mucosa due to anti-parietal cell antibodies. This review provides a comprehensive and up-to-date overview of autoimmune atrophic gastritis, reporting recent evidence on epidemiology, pathogenesis, diagnosis, clinical presentation, risk of malignancies, and management. The prevalence of AAG has been estimated at between 0.
View Article and Find Full Text PDFIdiopathic chronic intestinal pseudo-obstruction (CIPO) is associated with intestinal inflammation and malabsorption and may cause serum vitamin D deficiency. We aimed to assess whether there is an association between idiopathic CIPO and serum levels of 25-hydroxy-vitamin D. Consecutive patients with confirmed diagnosis of idiopathic CIPO were prospectively enrolled and matched with healthy controls by gender, age, and BMI.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to assess how effectively faecal calprotectin can differentiate between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), considering that their symptoms often overlap.
- - Researchers reviewed data from 17 studies including nearly 2,000 patients, finding that faecal calprotectin had a sensitivity of 85.8% and specificity of 91.7%, indicating it can be a reliable diagnostic tool.
- - The results showed that faecal calprotectin performed better in Western countries and at lower cut-off levels (≤50 μg/g), although most studies analyzed had a high risk of bias.