Publications by authors named "A Veerappan"
Article Synopsis
- Maize is crucial for regions facing drought, which can drastically reduce its yield due to oxidative stress.
- Selenium and zinc oxide nanoparticles have antioxidant properties that help protect maize during drought, but the effect of zinc selenide quantum dots (ZnSe QDs) needed research.
- This study found that using ZnSe QDs at 20 mg/L improved photosynthesis, reduced oxidative damage, and increased maize seed yield by 26%, suggesting that ZnSe could effectively mitigate drought effects.
Synthesis of cationic -acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of -acylation's role in membrane-disrupting activity.
RSC Med Chem
October 2024
Article Synopsis
- The rise of antimicrobial-resistant strains is a major threat to existing treatments, highlighting the need for new therapies.
- Researchers developed a new compound, QPyNATh, by modifying thiazolidine with fatty acids to enhance its ability to disrupt bacterial membranes, showing effective inhibition against Gram-positive bacteria while being selective for bacterial cells over human cells.
- Animal studies demonstrated that QPyN16Th significantly reduced MRSA infections in zebrafish and showed no signs of resistance developing, suggesting its potential as a biocompatible treatment for resistant bacterial infections.
Article Synopsis
- Reactive lesions in the oral cavity, like Peripheral Ossifying Fibroma (POF), arise from chronic irritation and are often found in younger individuals, predominantly females.
- This case report discusses a middle-aged male who had a notably large, asymptomatic POF located in the gum area of his lower back tooth.
- Surgical removal of the lesion was performed, and a histopathological examination confirmed the diagnosis, highlighting its unusual size and location.
Background: Particulate matter exposure (PM) is a cause of aerodigestive disease globally. The destruction of the World Trade Center (WTC) exposed first responders and inhabitants of New York City to WTC-PM and caused obstructive airways disease (OAD), gastroesophageal reflux disease (GERD) and Barrett's Esophagus (BE). GERD not only diminishes health-related quality of life but also gives rise to complications that extend beyond the scope of BE.
View Article and Find Full Text PDFAntibiotic resistance and re-emergence of highly resistant pathogens is a grave concern everywhere and this has consequences for all kinds of human activities. Herein, we showed that N-palmitoylethanolamine-derived cationic lipid (cN16E) had a lower minimum inhibitory concentration (MIC) against both Gram-positive and Gram-negative bacteria when it was loaded with Butea monosperma seed lectin (BMSL). The analysis using lectin-FITC conjugate labelling indicated that the improved antibacterial activity of BMSL conjugation was due to bacterial cell surface glycan recognition.
View Article and Find Full Text PDF