Changes in cardiac output and systemic arterial pressure after insertion of acrylic cement during trimetaphan, sodium nitroprusside and glycerol trinitrate-induced hypotension. A comparison with changes during normotension.

The effects of implantation of acrylic monomer on the cardiovascular response were studied in 37 patients undergoing hip arthroplasty and receiving high-dose fentanyl anaesthesia, under normotensive conditions or during hypotension induced by trimetaphan (TMP), sodium nitroprusside or nitroglycerine. Heart rate, mean arterial pressure (MAP), the ventricular stroke volume (SV) and the cardiac output (CO) were monitored before, and at 1, 2, 4, 6, and 8-min intervals after the insertion of the acrylic cement into the acetabulum or the neck of femur. There was a moderate decrease in MAP after insertion into the acetabulum under normotensive conditions and TMP-induced hypotension, while the reduction in pressure was significant after the cement's application in the femur.

Deliberate arterial hypotension in plastic surgery for the reduction of hypertrophic breast: a critical appraisal of surgical ischaemia and haemodynamic changes during sodium nitroprusside infusion.

Deliberate hypotension was used to attain surgical haemostasis in thirteen patients undergoing plastic and reconstructive surgery on breast, with an 0.01% sodium nitroprusside (SNP) infusion and concomitant deep neuroleptanaesthesia. The mean surgical haemorrhage was 217 ml in the hypotensive group and when compared with a group of 13 normotensive patients, in whom the average blood loss was 688 ml, the difference was highly significant.

Controlled hypotension in hip joint surgery. An assessment of surgical haemorrhage during sodium nitroprusside infusion.

Controlled hypotension, combined with light balanced anaesthesia, was employed during total hip replacement operations on 25 patients. Sodium nitroprusside (Nipride, Roche), in the form of a 0.01 per cent (100 micrograms/ml) infusion, was used as a hypotensive agent.