Publications by authors named "A Varughese"
Amoxicillin (AMX) is a commonly used antibiotic for treating infections and as a prophylactic antimicrobial agent, appreciated for its efficacy and favorable pharmacokinetics. Drug-induced acute kidney injury (AKI) significantly increases morbidity and mortality. Hemolytic uremic syndrome (HUS) is classified under thrombotic microangiopathies (TMAs), which are characterized by hemolysis, low platelet counts, thrombus formation in small vessels, and end-organ damage.
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- The mechanisms behind emotional responses to chronic pain are not well understood.
- In mice with chemotherapy-induced peripheral neuropathy (CIPN), licking affected areas becomes a strong coping mechanism, especially in response to cold stimuli.
- Research identified the lateral parabrachial nucleus (LPBN) as crucial in managing this licking behavior by responding to pain signals from the spinal cord and brain, highlighting the complex interaction between pain and emotional responses.
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- Patient safety science has changed a lot over the last 70 years with four frameworks: Safety-0, Safety-1, Safety-2, and Safety-3, which help understand how to keep patients safe better.
- In Safety-0, the focus is on preventing harm by improving staffing and education, while Safety-1 looks at both individual mistakes and system failures to create safer hospitals.
- Safety-2 and Safety-3 go further by emphasizing how doctors can adapt to changes and designing systems that help prevent harm, making the care process safer for patients.
Background and objectives Developing manual skills is important in dental education. Clinical skills can be taught via clinical demonstrations, and knowledge can be delivered through lectures. Performing dental restorations is an essential skill for dentists, which requires a comprehensive knowledge of the manipulation of the restorative materials.
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