Publications by authors named "A Vartanov"
Article Synopsis
- Inner speech is a key cognitive process, but its emotional aspects are not well understood.
- A study using fMRI involved 33 participants who listened to emotional phrases and practiced internally speaking them, either emotionally or neutrally.
- Results indicated that inner speech has an emotional component linked to the same brain structures as spoken speech, with the caudate nuclei playing a vital role in suppressing expression in inner speech.
The coronavirus disease 2019 (COVID-19) global pandemic has put an unprecedented strain on cancer care. The initial months were marred by fears of immunocompromised patients becoming opportunistic hosts to this deadly virus. We present a case of newly diagnosed high-grade B-cell lymphoma in a patient with COVID-19 and discuss the diagnostic and therapeutic challenges posed.
View Article and Find Full Text PDFSeveral PI3Kδ inhibitors are approved for the therapy of B cell malignancies, but their clinical use has been limited by unpredictable autoimmune toxicity. We have recently reported promising efficacy results in treating chronic lymphocytic leukemia (CLL) patients with combination therapy with the PI3Kδγ inhibitor duvelisib and fludarabine cyclophosphamide rituximab (FCR) chemoimmunotherapy, but approximately one-third of patients develop autoimmune toxicity. We show here that duvelisib FCR treatment in an upfront setting modulates both CD4 and CD8 T cell subsets as well as pro-inflammatory cytokines.
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