Publications by authors named "A Varadi"
The emergence of newer SARS-CoV-2 variants of concern (VOCs) profoundly changed the ICU demography; this shift in the virus's genotype and its correlation to lethality in the ICUs is still not fully investigated. We aimed to survey ICU patients' clinical and laboratory parameters in correlation with SARS-CoV-2 variant genotypes to lethality. 503 COVID-19 ICU patients were included in our study beginning in January 2021 through November 2022 in Hungary.
View Article and Find Full Text PDFBackground: Nonchromosomal congenital anomalies (NCAs) are the most common cause of infant mortality and morbidity. The role of maternal age is well known, although the specifics are not thoroughly elucidated in the literature.
Objective: To evaluate the role of maternal age in the incidence of NCAs and to pinpoint age groups at higher risk to refine screening protocols.
Introduction: Interstitial fibrosis and tubular atrophy are leading causes of renal allograft failure. Shear wave elastography could be a promising noninvasive method for providing information on the state of the kidney, with specific regard to fibrosis but currently available data in the literature are controversial. Our study aimed to analyze the correlation between shear wave elastography and various kidney dysfunction measures.
View Article and Find Full Text PDFArticle Synopsis
- Ovarian cancer is a significant health issue for women, often diagnosed late and tends to recur quickly, leading to a search for effective treatments like PARP inhibitors (PARPi).
- This study analyzed 16 randomized controlled trials involving 5,815 patients and found that PARPi therapy significantly improves progression-free survival (PFS) for both recurrent and newly-diagnosed ovarian cancer patients compared to placebo and chemotherapy.
- Despite a slight increase in severe side effects associated with PARPi therapy, these are manageable with dose adjustments, making PARPis a valuable treatment option for ovarian cancer.