Publications by authors named "A Vaporciyan"
Introduction: Children and young adults diagnosed with sarcoma often present with pulmonary metastases requiring wedge resection. It is important to balance the risk of pulmonary recurrence against the desire to limit resection of benign parenchyma. This study aims to determine the impact of resection margins on survival and recurrence among pediatric and young adult sarcoma patients.
View Article and Find Full Text PDFBackground And Objectives: Randomized clinical trials have shown that sub-lobar resection for clinical stage (cStage) IA non-small cell lung cancer (NSCLC) is non-inferior to lobar resection. We evaluated traditional and conditional survival differences between lobectomy, wedge resection, and segmentectomy in patients with cStage IA NSCLC.
Methods: The National Cancer Database (2004-2019) was queried for patients with cStage IA (≤ 2 cm) NSCLC who underwent upfront lobectomy, segmentectomy, or wedge resection.
Background: Neoadjuvant immune checkpoint inhibitors (ICIs) have improved survival outcomes compared with chemotherapy in resectable non-small cell lung cancer (NSCLC). However, the impact of actionable genomic alterations (AGAs) on the efficacy of neoadjuvant ICIs remains unclear. We report the influence of AGAs on treatment failure (TF) in patients with resectable NSCLC treated with neoadjuvant ICIs.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the feasibility and safety of active surveillance for patients with multiple ground glass opacities (GGOs) in the lungs, which are a common concern in medical imaging.
- A total of 337 patients, primarily older adults with a significant history of smoking, were enrolled and monitored over time, with each GGO documented via CT scans every 6 to 12 months.
- Preliminary findings suggest that active surveillance is a viable management option for patients, with ongoing assessments planned to evaluate long-term safety and outcomes over five years.