Hereditary angioedema: patient healthcare experiences within underrepresented racial and ethnic groups in the United States.

Background: Hereditary angioedema (HAE) is a rare disorder in which unpredictable angioedema attacks significantly impact patient quality of life (QoL). There is limited information regarding patient experiences and perspectives of HAE management within underrepresented racial and ethnic groups.

Objective: To gain insight into the experiences and perspectives of medical care and treatment for HAE among underrepresented racial and ethnic groups in the US.

Partisanship and the Pandemic: How and Why Americans Followed Party Cues on COVID-19.

The United States underperformed its potential in responding to the COVID-19 pandemic. The authors use original survey data from April 2020 to March 2022 to show that political partisanship may have contributed to this inconsistent response by distinguishing elites and citizens who took the crisis seriously from those who did not. This division was not inevitable; when the crisis began, Democrats and Republicans differed little in their viewpoints and actions relative to COVID-19.

Real-world clinical outcomes with avelumab in patients with Merkel cell carcinoma treated in the USA: a multicenter chart review study.

Background: Merkel cell carcinoma (MCC) is a rare, aggressive, cutaneous neuroendocrine neoplasm with annual incidence rates of 0.13-1.6 cases/100,000/year worldwide as of 2018.

New insights on the anatomy and ontogeny of the largest extinct freshwater turtles.

There are many questions regarding the largest freshwater turtle that ever existed, including how its morphology changed during its ontogeny and how a single ecosystem was able to support more than one group of giant turtles. Here, we report the first individual preserving an associated skull and shell for (currently the largest known side-necked turtle) and a nearly complete skull of found in Miocene rocks of the Tatacoa Desert in Colombia. These two specimens indicate that more than two large freshwater turtle species shared a single ecosystem during the middle Miocene in northern South America.