Tissue polypeptide antigen-specific (tps) and carcinoembryonic antigen (cea) levels in cancerous and precancerous lesions in human colon.

Serum levels of tissue polypeptide antigen specific (TPS), a cytokeratin 18 marker, were determined and compared with serum levels of carcinoembryonic antigen (CEA) in 45 patients with colon adenocarcinoma and in 34 patients with benign diseases (adenomatous polyps and ulcerative colitis) at the time of diagnosis. In colon carcinoma patients 58% had an elevated TPS level (cut-off 100 U/l) and 53% had an elevated CEA level (cut-off 3.0 ng/ml).

Tps in serum and urine of egyptian bladder-cancer patients.

TPS levels were determined in the serum and urine of 136 Egyptian patients with infiltrating bladder cancer and compared with the levels in 45 normal controls and 45 patients with urinary tract Bilharziasis. At 95% specificity the sensitivy in bladder cancer patients in serum and urine was 34.6% and 96.