Publications by authors named "A Van Der Wel"
Article Synopsis
- - The study examined the real-world effects of stereotactic body radiotherapy (SBRT) in patients with stage I non-small cell lung cancer (NSCLC), focusing on acute toxicity and 90-day mortality rates among 7,279 patients treated between 2017 and 2021.
- - Acute toxicity occurred in 3.8% of patients, while 90-day mortality was at 1.7%, with certain factors like age, sex, and lung function impacting these outcomes.
- - The findings suggest that SBRT has a low rate of acute toxicity and acceptable mortality, with developed prediction models aiding in identifying patients at higher risk for adverse effects.
Aims: The impact of maternal metformin use during pregnancy on fetal, infant, childhood and adolescent growth, development, and health remains unclear. Our objective was to systematically review the available evidence from animal experiments on the effects of intrauterine metformin exposure on offspring's anthropometric, cardiovascular and metabolic outcomes.
Methods: A systematic search was conducted in PUBMED and EMBASE from inception (searched on 12th April 2023).
Aim: To investigate the association between continuous glucose monitoring (CGM) metrics and perinatal outcomes in insulin-treated diabetes mellitus in pregnancy.
Materials And Methods: In a post-hoc analysis of the GlucoMOMS randomized controlled trial, we investigated the association between the metrics of an offline, intermittent CGM, glycated haemoglobin (HbA1c) and perinatal outcomes per trimester in different types of diabetes (type 1, 2 or insulin-treated gestational diabetes mellitus [GDM]). Data were analysed using multivariable binary logistic regression.
Introduction: Chemoradiotherapy (CRT) is the standard of care in inoperable non-small-cell lung cancer (NSCLC) patients, favoring concurrent (cCRT) over sequential CRT (seqCRT), with adjuvant immunotherapy in responders. Elderly and frail NSCLC patients have generally been excluded from trials in the past. In elderly patients however, the higher treatment related morbidity of cCRT, may outweigh the possible lower tumor control of seqCRT.
View Article and Find Full Text PDFVaccine development for Plasmodium vivax, an important human relapsing malaria, is lagging behind. In the case of the most deadly human malaria P. falciparum, unprecedented high levels of protection have been obtained by immunization with live sporozoites under accompanying chemoprophylaxis, which prevents the onset of blood-stage malaria.
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