Publications by authors named "A Vadillo-Bermejo"
Article Synopsis
- The study aimed to analyze the relationship between Alzheimer's disease (AD) and various autoimmune diseases by comparing patients with these conditions to the general population.
- A total of over 1 million patient records were reviewed, finding that 5 out of 12 autoimmune diseases had a significant association with an increased prevalence of AD.
- The research suggests a potential link between certain autoimmune diseases and Alzheimer's, but further studies are necessary to confirm these findings and understand the reasons behind the association.
Introduction: Myasthenia gravis (MG) and Alzheimer's disease (AD) are two of the most important diseases where the dysregulation of acetylcholine activity plays a crucial role. In the first, this dysregulation happens at the level of the neu-romuscular junction and in the second, in the central nervous system (CNS).
Aim: To analyze the possible relationship between these two pathologies, analyzing the prevalence and the odds ratio of AD within patients previously diagnosed with MG.
Article Synopsis
- The study focused on the prevalence of ataxia and hereditary spastic paraplegia in Spain, involving 1933 patients from various regions between 2018 and 2019.
- Results showed that ataxia was more prevalent (70.9%) compared to hereditary spastic paraplegia (29.1%), with overall prevalence rates of 5.48 and 2.24 cases per 100,000 population, respectively.
- A significant portion of patients (47.6%) lacked a genetic diagnosis, highlighting the need for improved healthcare resources and awareness for these rare disorders.
Article Synopsis
- - The study aimed to assess the prevalence of ataxia and hereditary spastic paraplegia in Spain during 2019, finding 1,809 affected patients with an average age of 53.64 years.
- - Results showed that 70.9% of patients had ataxia, with prevalence rates of 5.48 cases per 100,000, while hereditary spastic paraplegia had a prevalence of 2.24 cases per 100,000.
- - The study highlighted that genetic causes were unidentified in nearly half of the patients, emphasizing the need for better healthcare resources and awareness about these neurodegenerative disorders.