Publications by authors named "A V Zorin"
Article Synopsis
- Carbasugars are carbohydrate derivatives where the ring oxygen is replaced by a methylene group, resulting in a molecule that resembles traditional sugars but behaves differently.
- These compounds, including unsaturated cyclohexenols and various sugars, are found in both bacteria and humans, serving as important neurotransmitters like inositol trisphosphate.
- The article reviews various synthesis methods for carbasugars and their derivatives, highlighting their significance in research areas such as enzyme inhibition, lectin-binding, and potential treatments for HIV and cancer.
Aim: To study demographic and clinical characteristics and to give a comparative description of the functional and hemodynamic status, profile of concomitant pathology in patients with various forms of pulmonary arterial hypertension (PAH), and chronic thromboembolic pulmonary hypertension (CTEPH) according to the Russian National Registry.
Methods: During the period from January 01, 2012, till January 01, 2019, 1105 patients aged >18 years with verified diagnosis of PAH and CTEPH, who were subsequently observed at 15 PH expert centers of the Russian Federation in the 52 provinces, are included in the Russian registry on the basis of the Federal State Budgetary Institution of Cardiology of the Ministry of Healthcare of Russia. All newly diagnosed patients ( = 727) were entered into the registry database (NCT03707561).
The amount of omics data in the public domain is increasing every year. Modern science has become a data-intensive discipline. Innovative solutions for data management, data sharing, and for discovering novel datasets are therefore increasingly required.
View Article and Find Full Text PDFThe number of bariatric (weight loss) surgeries have increased steadily in the past decade. Along with the tangible benefit of this treatment, there is a risk for postoperative complications, the main cause of which is impaired absorption of nutrients. The paper describes polyradiculoneuropathy running as a type of Guillain-Barré syndrome.
View Article and Find Full Text PDFAim: To examine the antihypertensive effect of the synthetic analogue of the endogenous nitric oxide donors in patients with grades 2-3 hypertension and uncomplicated hypertensive crisis (HC).
Subjects And Methods: The study included 30 male patients aged 35 to 73 years (mean age 55.5 ± 10.