[Prevalence and prognostic value of gastroenterological manifestations of COVID-19: data from the Russian University Clinic].

Aim: Assessment of the prevalence and prognostic value of gastroenterological manifestations in patients with COVID-19.

Materials And Methods: A single-center retrospective cohort study was carried out. Only cases with laboratory confirmed detection of SARS-CoV-2 virus RNA using polymerase chain reaction in oro-/nasopharyngeal smear samples were subject to analysis.

[Antibiotic resistance of Helicobacter pylori in the European part of the Russian Federation: first results].

Aim: Determine the primary antibiotic resistance of Helicobacter pylori (H. pylori) strains isolated from patients living in the European part of the Russian Federation.

Materials And Methods: As part of a clinical laboratory study, from 2015 to 2018, 27 gastrobiopsy samples obtained from H.

[The efficacy and safety of quadruple therapy without bismuth (concomitant therapy) in the treatment of patients with Helicobacter pylori - associated gastric and duodenal peptic ulcer disease].

Aim: Evaluation of the efficacy and safety of quadrupletherapy without bismuth (concomitant therapy) in patients with Helicobacter pylori - associated gastric ulcer and duodenal ulcer in the framework of a comparative research in the population of patients in Russia.

Materials And Methods: A prospective randomized trial was conducted, which included 210 patients with H. pylori - associated gastric/duodenal ulcer without complications.

Design of Nanosomal Form of Aprotinin.

Liposomes containing aprotinin were produced by the phase inversion technique and purified by gel filtration. Aprotinin inclusion was assessed fluorescence labeling of the protein. The size of obtained liposomes was 212±35 nm and aprotinin concentration in the liposomal suspension was 3000 KIU/ml.