Publications by authors named "A V Wewer"
Article Synopsis
- Inflammatory bowel diseases (IBD) like Crohn's disease and ulcerative colitis are chronic conditions affecting the gastrointestinal tract, and a study has been launched in Denmark to explore their varied progression and treatment responses.
- The IBD Prognosis Study is a comprehensive, population-based research involving newly diagnosed IBD patients of all ages from a region covering around 1.05 million people, following strict diagnostic criteria for accurate identification.
- The study’s methods include regular clinical assessments, various imaging techniques, and systematic sample collection to analyze biomarkers, microbiome, and genetic information, alongside evaluating the impact of environmental factors and extraintestinal complications.
Background: Our aim was to characterize the biochemical markers at diagnosis in patients with inflammatory bowel disease (IBD), to assess the utility of these to predict disease course and investigate if genotype influences biochemical markers of inflammation.
Summary: Patients were included from a population-based pediatric IBD cohort from Eastern Denmark. Data on biochemical markers and medical as well as surgical treatment were registered at diagnosis, 30 days, 6 and 12 months after diagnosis.
Background: Risk benefit strategies in managing inflammatory bowel diseases (IBD) are dependent upon understanding the risks of uncontrolled inflammation vs those of treatments. Malignancy and mortality in IBD have been associated with disease-related inflammation and immune suppression, but data are limited due to their rare occurrence.
Aim: To identify and describe the most common causes of mortality, types of cancer and previous or current therapy among children and young adults with paediatric-onset IBD.
Syndromic diarrhea/tricho-hepato-enteric syndrome (SD/THE) is a rare congenital enteropathy with seven main clinical features: intractable diarrhea of infancy, hair abnormalities, intrauterine growth restriction (IUGR), facial dysmorphism, immune dysfunction, and liver and skin abnormalities. SD/THE is caused by mutations in TTC37 or SKIV2L, two genes encoding components of the human SKI complex. To date, approximately 50 SD/THE patients have been described with a wide spectrum of mutations, and only one recurrent mutation has been identified in independent families.
View Article and Find Full Text PDFValidation of psychomotor tasks by Simbionix LAP Mentor simulator and identifying the target group.
Minim Invasive Ther Allied Technol
October 2017
Background: This study addresses target group reliability and task validity for training on a laparoscopic simulator.
Material And Methods: Data were collected on 64 participants prospectively at the Department of OB/GYN, University Hospitals Schleswig-Holstein, Campus Kiel. The Simbionix LAP Mentor for laparoscopic simulation was used to test trainees.