Publications by authors named "A V Vrublevskiĭ"

Comparison of velocity parameters of blood flow and absolute coronary reserve (absCR) in the left anterior descending and posterior interventricular coronary arteries (ADCA and PICA) with calculation of relative coronary reserve (relCR) and determination of its normative values was carried out with the help of transthoracic echocardiography in 29 healthy volunteers (mean age 40+/-13 years). Assessment of the role of absCR and relCR in ADCA in diagnostics of hemodynamically significant stenoses of this vessel was performed in 88 patients with syndrome of cardiac pain (mean age 40+/-12 years). Coronary angiography was used as a reference method.

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Analysis of possibilities of transthoracic echocardiography (TTEchoCG) diagnosis of hemodynamically significant stenoses of anterior descending and right coronary arteries (ADCA and RCA) based on Doppler assessment of coronary reserve (CR) was carried out in 73 patients with cardiac pain syndrome (mean age 48+/-7 years, 60 men, 13 women). As a referent method we used coronary angiography. Coronary blood flow at baseline and during administration of a vasodilator (dipyridamole up to 0.

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Comparative analysis of possibilities of transthoracic echocardiography (TTE) and coronary angiography in diagnosis of chronic occlusions of anterior descending (ADA), circumflex (CA), and right coronary (RA) arteries was carried out in 100 patients (90 men, 10 women, mean age 51 +/- 11 years). With the help of TTE we analyzed direction, structural and temporal parameters of coronary blood flow in zones of potential epicardial and intramyocardial collateral filling: for ADA - in distal segment (dADA) and septal branches (SBADA), for CA - in obtuse marginal branches (OMB), for RCA - in posterior interventricular artery (PIA) and septal branches (SBRCA). We found that TTE was a sensitive and highly specific method of diagnosis of ADA and RCA occlusions, but did not allow to diagnose adequately occlusions of CA.

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The lecture contains: presentation of possibilities of ultrasound and tomographic methods of investigation in visualization of major coronary arteries; consideration in a comparative aspect of main advantages, disadvantages and limitations of these methods in diagnostics of coronary atherosclerosis; analysis of indications for application and perspectives of their use in everyday clinical practice in patients with a diagnosis of possible or verified ischemic heart disease.

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The lecture deals with methodological aspects and diagnostic potential of the use of novel ultrasound technologies -- transesophageal and transthoracic doppler ultrasonography of coronary arteries for noninvasive assessment of coronary blood flow and coronary reserve. It contains detailed description of technique of visualization of coronary arteries from transesophageal and from transthoracic approaches and interpretation of dopplero-graphic parameters of laminar and turbulent coronary flows. Diagnostic role of the use of contrast echo imaging of coronary arteries is also discussed and dopplero-graphic criteria of occlusion and hemodynamically significant coronary artery stenosis as well as characteristics of normal and lowered coronary reserve are presented.

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