Publications by authors named "A V Vanlander"
Article Synopsis
- This study is about how a specific gene (TXNRD2) impacts adrenal cortisol production, which is important for our body's stress response.
- Researchers looked at a patient with a rare gene change that caused problems with cortisol production, leading to health issues.
- They found that the gene mutation led to increased harmful substances in the body and reduced the ability to make cortisol, which is vital for health.
Non-pancreatic periampullary tumors have long been neglected, leading to blurred adjuvant treatment strategies. Recent research, like the ISGACA group's study, is uncovering nuances in chemotherapy efficacy for these diverse cancers. Tailored approaches show promise, with artificial intelligence (AI) aiding in personalized treatment plans.
View Article and Find Full Text PDFBackground: Congenital myasthenic syndromes (CMS) are a group of genetic disorders characterized by impaired neuromuscular transmission. CMS typically present at a young age with fatigable muscle weakness, often with an abnormal response after repetitive nerve stimulation (RNS). Pharmacologic treatment can improve symptoms, depending on the underlying defect.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to compare the outcomes of laparoscopic and open major liver resection (hemihepatectomy) primarily for cancer patients, focusing on functional recovery time and other health-related factors.
- In a multicenter trial, 332 patients underwent surgery, with laparoscopic surgeries resulting in faster functional recovery (4 days vs. 5 days) and higher quality of life scores compared to open surgeries.
- The laparoscopic approach also led to a shorter time to start adjuvant systemic therapy for cancer patients, without negatively affecting resection margin status or overall cancer outcomes.
Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is clinically diverse, and children have a low risk of developing severe coronavirus disease 2019 (COVID-19). However, children with chronic diseases have a potentially increased risk.
Methods: We performed a prospective surveillance study with longitudinal serum SARS-CoV-2 anti-nucleocapsid antibody quantification and questionnaires in pediatric tertiary care patients during the first waves of the COVID-19 pandemic (November 2020-September 2021).