The species of is the most common human pathogen of the genus, which can be associated with acute appendicitis, infections of the bloodstream, the peritoneal cavity, cerebrospinal fluid, inflammatory bowel disease, and in general, bacteremia. According to the literature, has destructive activity to a wide range of toxic chemical compounds, including chlorobenzenes. The specified strains were isolated from the soil of the organochlorine waste landfill, where hexachlorobenzene (HCB) was predominant.
View Article and Find Full Text PDFIn this study, we investigated compounds of plant and mushroom origin belonging to Traditional Chinese Medicine (TCM) and to Traditional Tibetan Medicine (TTM): a sandy beige mushroom Murr, commonly known as Huaier/TCM as well as Ershiwuwei Songshi Wan and Qiwei Honghua Shusheng Wan, which both belong to TTM. We aimed to study the efficacy of TTM and TCM in hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) . TCM and TTM were tested either as a monotherapy, or in combination with standard therapeutics: sorafenib for HCC treatment and gemcitabine for CCA.
View Article and Find Full Text PDFTPX2 (Targeting Protein for Xklp2) is an evolutionary conserved microtubule-associated protein important for microtubule nucleation and mitotic spindle assembly. The protein was described as an activator of the mitotic kinase Aurora A in humans and the AURORA1 (AUR1) kinase. In contrast to animal genomes that encode only one TPX2 gene, higher plant genomes encode a family with several gene members (TPXL).
View Article and Find Full Text PDFPeculiarities of growth of the strains of two species of microscopic fungi Aspergillus versicolor and Paecilomyces lilacinus were analyzed under exposure to chronic irradiation. It was shown that the rate of radial growth increased nonuniformly in the range of doses from 0 to 250 mGy but with maximums at a certain dose of radiation. It was shown that the absorbed dose of radiation to 2 Gy did not influence the survival of investigated strains in comparison with the control ones without irradiation.
View Article and Find Full Text PDF