[Evaluation of metabolic disorders in surgical patients].

The paper treats the problems of metabolism derangement in surgical patients. Special emphasis is laid on the correction of metabolic abnormalities in the pre- and postoperative periods and on the use of parenteral feeding in surgical complications: incompetence of anastomosis sutures, peritonitis, intestinal fistulas, and so forth. The authors define the role of the drugs of directed action in such a severe pathology as hepatorenal insufficiency.

[The effect of surgical trauma on the metabolism of essential fatty acids in patients with cancer of the esophagus and stomach].

The dynamics of levels of essential fatty (linolic and arachidonic) acids in blood plasma and erythrocytes as well as that of free fatty acids fraction versus duration of surgery was assessed by gas chromatography in 49 patients with cancer of the esophagus and gastric cardia. Surgical procedures lasting longer than 5 hours are followed by overmobilization of essential fatty acids from body lipids their endogenous store being depleted. As a result, a double increase in the level of free arachidonic acid, an immediate prostaglandin precursor, develops to satisfy the body's augmented requirements in essential fatty acids due to application of aggressive surgical procedures.

[Correction of osmotic-volume status by parenteral feeding of patients with stomach cancer].

The paper discusses the interrelationship between osmo-volume parameters of homeostasis as well as the role of adequate parenteral nutrition in correction of surgery-associated disorders in gastric cancer patients. The study included 123 such cases. The baseline circulating blood volume and that of blood components was found decreased whereas blood serum osmotic index elevated.

[The use of artificial feeding during the resuscitation of heart surgery patients].

The data on the use of various schemes of artificial nutrition (AN) are reviewed in 137 patients with postoperative complications after cardiopulmonary bypass surgery. It has been established that AN as part of a complex therapy of patients in the early postoperative period has a correcting effect on metabolism and promotes the improvement of the patients' clinical condition. Rational combination of parenteral and enteral tube nutrition ensures adequate AN of cardiosurgical patients in the early postoperative period.

[The effect of parenteral feeding on the metabolism of arachidonic acid in patients with cancer of the esophagus and the stomach].

Blood plasma and erythrocyte level of arachidonic acid (C20:4) and blood plasma level of its two metabolites (6-keto-PGF1 alpha and TXB2) have been investigated in 24 patients with esophageal and gastric cancer. In the preoperative period and during 8-10 days postoperatively 12 patients were on "glucose" energy supply (group I) and 12 patients were on "lipid" energy supply (group II). Daily calorie intake was 30-35 kcal/kg.