[Endometrial hyperplastic changes and precancerous conditions: terminology and classification].

The paper presents the data available in the literature on the debated aspects of the terminology and classification of endometrial hyperplastic lesions, precancerous conditions of the corpus uteri. Particular emphasis is laid on the low reproducibility of the histological diagnosis of endometrial changes in accordance with the WHO criteria. Focus is on the disadvantages of a morphometric study for diagnosing endometrial intraepithelial neoplasia.

[Characteristic of sorption properties of skeletal muscle nuclei in the normal state and with E-avitaminotic muscular dystrophy].

Sorption properties of skeletal muscles nuclei in rabbits in normal state and with E-avitaminosis were studied using organic dyes: neutral red (cationic) and turquoise direct light-fast "K" (anionic) and the influence of calcium-modified membrane of nuclei on their sorption. The nuclear surface is established to have both positive and negative charged groups sorbing turquioise direct and neutral red, respectively. The maximum volume of the dyes binding and the dissociation constants of the membrane-dye complex are estimated.

[Molecular organization of Mg2+, Ca2+-ATPase of sarcoplasmic reticulum].

The article deals with the results of studies on the structure and properties of discrete sites in a molecule of sarcoplasmic reticulum Mg2+, Ca2+-ATPase obtained during its fragmentation in the process of its limited hydrolysis by trypsin. It is established to contain three fragments with the molecular mass of 45 000, 30 000 and 20 000 Daltons. Some properties of these fragments are determined by the amino acid analysis, inhibitory analysis with application of radiactive labels and also of immunochemical analysis.

[Effect of SH-reagents on ATPase systems of rabbit skeletal muscle nuclei].

The influence of sulfhydryl reagents on ATPase systems of rabbit sceletal muscles nuclei was studied. It is found that p-ChMB at low concentration similarly inhibits both Mg2+- and Mg2+, Ca2+-ATPases. p-ChMB at higher concentrations inhibits completely Mg2+, Ca2+-ATPase, while Mg2+- ATPase--only by 60%.

[Electron-cytochemical study of the localization and properties of ATPases in the isolated nuclei of rabbit skeletal muscle under normal conditions and in experimental muscular dystrophy].

The properties and localization of ATPase system in nuclei of skeletal muscle of normal rabbit and of those with experimental muscle dystrophy were studied by electron cytochemistry. The product of cytochemical reaction of ATP hydrolysis, which is a marker of ATPase activity localization in nuclear ultrastructures, was detected on the nuclear membrane, in chromatin and in the nucleolus, ATPase activity in the nuclei was detected in the presence of both, Mg2+ and Ca2+. Addition to the incubation medium, originally containing Mg2+, Na+ and K+, resulted in an increased formation of the product reaction in all the nuclear ultrastructures in both in the norm and under experimental muscle dystrophy.