Publications by authors named "A V Shekhter"
Modern otology faces challenges in treating tympanic membrane (TM) perforations. Instead of surgical intervention, alternative treatments using biomaterials are emerging. Recently, we developed a robust collagen membrane using semipermeable barrier-assisted electrophoretic deposition (SBA-EPD).
View Article and Find Full Text PDFRenal cell carcinoma is a significant health burden worldwide, necessitating accurate and efficient diagnostic methods to guide treatment decisions. Traditional pathology practices have limitations, including interobserver variability and time-consuming evaluations. In recent years, digital pathology tools emerged as a promising solution to enhance the diagnosis and management of renal cancer.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how the surface texture of biomaterial implants affects inflammatory and fibrotic reactions in surrounding tissues.
- Researchers created three types of implants from polylactide granules of varying diameters and implanted them in chinchilla rabbits to analyze tissue response over time.
- Results showed that larger granule implants led to a milder inflammatory response and slower capsule formation, highlighting the importance of surface texture in preventing complications like capsular contracture.
Background: There is growing interest to application of regenerative medicine approaches in otorhinolaryngological practice, especially in the framework of the therapy of vocal fold (VF) scar lesions. The used conservative and surgical methods, despite the achieved positive outcomes, are frequently unpredictable and do not result in the restoration of the VF's lamina propria's structure, which provides the mechanical properties necessary for vibration. In this connection, the aim of this study was to ascertain the safety and efficacy of a bioequivalent in the treatment of VF scars using a rabbit model of chronic damage.
View Article and Find Full Text PDFThe analysis of the microvasculature and the assessment of angiogenesis have significant prognostic value in various diseases, including cancer. The search for invasion into the blood and lymphatic vessels and the assessment of angiogenesis are important aspects of oncological diagnosis. These features determine the prognosis and aggressiveness of the tumor.
View Article and Find Full Text PDF