Publications by authors named "A V Semenkov"

Objective: Evaluation of the analgesic, opioid-sparing, anti-inflammatory and adverse effects of the diclofenac and orphenadrine (Neodolpasse) fixed combination for analgesia in the postoperative period of surgical cancer patients.

Material And Methods: A randomized, single-center, prospective, comparative study evaluated two analgesic regimens in 40 cancer patients undergoing various open cavity surgeries, including extensive combined interventions associated with the resection of 3 or more organs. The study was conducted following the transfer from the ICU to the surgical department during the early activation period, within the first two postoperative days.

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Article Synopsis
  • The text discusses a rare clinical case involving two types of cancer: distal cholangiocarcinoma in the bile duct and an intraductal papillary mucinous tumor linked to ductal adenocarcinoma of the pancreatic tail.
  • This case is considered unique as there are no documented instances of similar multiple primary malignant tumors in existing literature.
  • It emphasizes that a definitive diagnosis of simultaneous pancreatobiliary cancers can only be achieved through intraoperative biopsy and detailed analysis of the affected organs, as the cancers share similar histological and immunohistochemical features.
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Parenchyma- sparing liver resections are aimed at maximizing the possible preservation of parenchyma not affected by the tumor - a current trend in hepatopancreatobiliary surgery. On the other hand, a prerequisite for operations is to ensure their radicality. To effectively solve this problem, all diagnostic imaging methods available in the arsenal are used, which make it possible to comprehensively solve the issues of perioperative planning of the volume and technical features of the planned operation.

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Surgery is one of the leading treatment methods of patients with primary or recurrent malignant neoplasms in the thoracic or abdominal cavity. Extensive abdominal interventions are accompanied by such adverse outcomes as blood loss, hypoxia, inflammation, blood clotting abnormality, emotional and cognitive disorders, that increases the incidence of serious complications and worsens the treatment outcome and life quality in weakened oncological patients. Multimodal pre-rehabilitation before surgery can significantly decrease the incidence and severity of postoperative complications.

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The purpose of the study was a systematic review of current trends in preoperative planning of surgery for liver tumors. These data will be valuable to determine the advantages and disadvantages of 3D modeling, augmented reality technology and 3D printing in preoperative planning of surgery for focal liver lesions.

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