Publications by authors named "A V Samodova"
Article Synopsis
- The study investigates how the immune system and blood transport components of people in the Arctic region of Russia adapt to environmental stressors, revealing the body's resilience and functionality.
- The research analyzed blood samples from 191 Arctic residents, measuring indicators like hemoglobin levels, immune cell activity, and cytokine concentrations, using various statistical methods.
- Findings showed high rates of erythrocytosis, thrombocytosis, and leukocytosis among locals, while highlighting reduced active phagocytes and specific lymphocyte populations, alongside increased levels of pro-inflammatory cytokines and circulating immune complexes.
Polyphenols (PP) found in brown algae are known for their wide range of biological activities including noteworthy antitumor properties. This article presents a method for obtaining an active polyphenolic extract from the Arctic alga Fucus vesiculosus with 98% purity and radical scavenging activity equivalent to 862 mg of ascorbic acid per gram of extract. Immunostimulant effects of polyphenols were assessed in vitro using venous blood from two groups of people: healthy people (HP) and people with chronic undifferentiated lymphocytic leukemia (LP).
View Article and Find Full Text PDFSpecific antibodies to food antigens are detected both in healthy individuals and in various pathologies, including those of the gastrointestinal tract, neuro- and autoimmune diseases. In fact, there are no studies concerning the level of specific IgG to food antigens in metabolic syndrome. A comparative analysis of the concentration of specific IgG to food antigens in patients with metabolic syndrome and healthy people was carried out.
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- The study aimed to investigate the immune status of the Kola Saami and Russians living in the extreme climates of the Far North, focusing on how climate and genetic factors affect immunological reactivity.
- Researchers conducted a detailed blood analysis on 67 Saami and 81 Russians, examining various immune cells, cytokines, and antibodies through advanced immunological techniques.
- Results indicated that the Saami exhibited lower leukocyte counts and deficiencies in certain immune components, while the Russians showed higher levels of various immune markers, suggesting distinct immune profiles between the two populations.
The paper presents data on the impacts of the content of ApoA-I in peripheral blood on the state of immune homeostasis in people living in extreme climatic conditions of the Arctic. From the village of Revda, Murmansk region, 191 people were examined, 160 women and 31 men, aged from 21 to 55 years. The analysis of the results was carried out depending on the level of ApoA-I content: 111 examined people had a low content of ApoA-I (< 115 mg/dl) and 80 people had a concentration of ApoA-I - within the physiological norm (115-220 mg/dl).
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