[Relationship between emotional stress in female residents of the city of Chapaevsk and toxicological and genetic values].

The severity of stress was evaluated in 45 female residents of the town of Chapaevsk (3 groups, 14-15 females each, with different levels of exposure to dioxins) using 5 standard psychological questionnaires. The results of testing were correlated to plasma dioxin concentrations and levels of chromosome aberrations in peripheral blood lymphocytes of the same donors. The results indicate that the groups differed by the degree of stress, the highest level being observed in women occupationally exposed to dioxins.

[Experience in the study of the effects of lead on the health status of children in Belovo].

Lead releases in Belovo town containing metallurgy enterprise had reached 120 tons/year earlier, but in recent years have decreased to 9 tons/year. Reduction of the production induced decrease of lead levels in the ambient air from 0.7-2.

[Value of estimation of stress during human toxico-genetical investigations].

The paper presents the monitoring results of the genetic and mental status of workers from 2 plants of Yaroslavl. The groups of the examinees were formed in terms of unhealthy working conditions and residence in clean or polluted areas of the city. The individuals working under harmful and living under unfavourable environmental conditions were found to be more commonly acute or chronically stressed or fatigable than the control workers.

Heterogeneous distribution of D1, D2 and D5 receptor mRNAs in monkey striatum.

The primate striatum has a compartmental organization reflected both in the topography of its afferent projections and in the segregation of its morphologically similar but neurochemically distinct efferent neurons. Discretely projecting mesostriatal neurons release dopamine (DA) which modulates the responses of striatal neurons to other afferent inputs. Multiple DA receptor (DAR) subtypes have been cloned and characterized and mapping their cellular expression is crucial for understanding the influence of DA on striatal function.

Cloning and characterization of the human GnRH receptor.

A cDNA encoding the human GnRH receptor (GnRHR) has been cloned and functionally expressed in both Xenopus oocytes and COS-1 cells. The 2160 bp cDNA encodes a 328 amino acid protein with a predicted amino acid sequence that is 90% identical to that of the mouse GnRHR (Tsutsumi et al. (1992) Mol.