[Vegetative disbalance in pathogenesis of metabolic syndrome].

The aim of the work was to elucidate peculiarities of neurovegetative mechanisms underlying cardiovascular regulation in patients with metabolic syndrome (MS) compared with healthy subjects and patients with arterial hypertension (AH). 46 patients presented with AH without obesity and metabolic disturbances, 42 with MS. 24-hour AD and ECG monitoring was performed and cardiac rhythm variability indices (CVI) were calculated.

[Influence of nebivolol on left ventricular remodeling in patients with arterial hypertension without chronic heart failure].

In the recent years the problem of heart remodeling under drugs in patients with arterial hypertension (AH) have been extensively discussed. The beta-blocker of the third generation nebivolol is known as a good antihypertensive agent. The aim of our study was to evaluate effects of nebivolol on structural and functional parameters of cardiac remodeling in patients with AH without heart failure.

[Changes of the thyroid hormone status in children with cerebral palsy and other neurological pathology].

Content of thyroid hormones (T3 and T4) and thyrotropin (TTG) hormone in blood plasma has been studied in 142 children with neurological pathology (cerebral palsy, perinatal CNS lesion). In most cases, there was a significant increase of T3 and T4 and reduction of TTG as compared to control group of healthy children. The changes of thyroid hormones content depended on the patient's age and severity of a pathological condition.

[Biochemical changes of red blood cells in children with cerebral palsy and other organic brain disorders].

One hundred and twenty-five children with cerebral palsy (n = 108) and organic CNS lesions (n = 17) have been studied. A control group included 30 children without any neurological lesions. Lipids and phospholipids spectra, Ca, Mg- and Na, K-ATPases, intensity of red blood cells lipid peroxidation and erythrocyte free magnesium content have been determined.

[Lipid peroxidation in neurological pathology in children].

The intensity of lipid peroxidation (LPO) was studied by the content of the listed below in erythrocytes of children with neurological pathology: diene conjugates, trienketones and LPO products. Intensified LPO processes were registered in children with neurology and primarily in those with cerebral spastic infantile paralysis (CSIP). The detected changes in the LPO products of erythrocyte membranes depended on a disease variation on an intellectual development of sick child.