Publications by authors named "A V Perruccio"

Article Synopsis
  • The study looks at different types of cells in the infrapatellar fat pad (IFP) of the knee and how they change with knee osteoarthritis (KOA), gender, and obesity.
  • Researchers used advanced techniques to analyze over 80,000 cell nuclei from both healthy and KOA patients.
  • They discovered that certain cells behave differently based on these conditions, and they found important differences in the way fibroblast cells act in people with different body types.
View Article and Find Full Text PDF

Objective: The purpose of the study is to examine the relationship between osteoarthritis (OA) and joint symptoms typical of OA and labor force participation.

Methods: Data are from the baseline questionnaire of the Canadian Longitudinal Study on Aging for respondents aged 45 to 74 years at baseline (n = 24,427). Individuals were categorized into one of five mutually exclusive arthritis status groups: diagnosed OA, diagnosed other type of arthritis, two to three symptomatic joint sites and no diagnosed arthritis, one symptomatic joint site and no diagnosed arthritis, and no arthritis and no joint symptoms.

View Article and Find Full Text PDF

Objective: Osteoarthritis (OA) is frequently perceived as a disease of the elderly and an inevitable result of aging. Because OA studies often are restricted to older adults, there is limited information on OA in younger adults. This study describes the burden of OA across a wide age range and compares younger and older adults.

View Article and Find Full Text PDF

Few studies have examined diabetes impact on total joint arthroplasty (TJA) outcomes, with variable findings. We investigated the association between diabetes and post-TJA physical function and pain, examining whether diabetes impact differs by sex and BMI. Patient sample completed questionnaires within 3 months prior to hip or knee TJA for osteoarthritis (OA) and 1-year post-surgery.

View Article and Find Full Text PDF