Publications by authors named "A V Nesterenko"

One of the challenging problems in the research and development of vibration sensors relates to the formation of Ohmic contacts for the removal of an electrical signal. In some cases, it is proposed to use arrays of carbon nanotubes (CNTs), which can serve as highly elastic electrode materials for vibration sensors. The purpose of this work is to study the effect of a current-collecting layer of CNTs grown over silicon on the properties of a lead zirconate titanate (PZT) film, which is frequently employed in mechanical vibration sensors or energy harvesters.

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Atomistic molecular dynamics (MD) simulations are a much-used tool for investigating the structure and dynamics of biomembranes with atomic resolution. The validity of the representations obtained is determined by the accuracy and realism of the MD model (force field). Here, we evaluated the proprietary OPLS4 force field of Schrödinger, Inc.

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Article Synopsis
  • Embryonic scaling is a unique biological phenomenon where embryos adjust their spatial structure according to their size, initially described in sea urchins.
  • Recent research has aimed to understand the role of specific genes, termed "scalers," which are crucial in regulating morphogen concentration gradients in correlation with embryo size.
  • The findings confirm that scalers, including the gene Mmp3, exist in various reaction-diffusion system models and play a vital role in maintaining gradient scaling across different embryonic types.
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Tools based on artificial intelligence (AI) are currently revolutionising many fields, yet their applications are often limited by the lack of suitable training data in programmatically accessible format. Here we propose an effective solution to make data scattered in various locations and formats accessible for data-driven and machine learning applications using the overlay databank format. To demonstrate the practical relevance of such approach, we present the NMRlipids Databank-a community-driven, open-for-all database featuring programmatic access to quality-evaluated atom-resolution molecular dynamics simulations of cellular membranes.

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Article Synopsis
  • During gastrulation and neurulation in vertebrate embryos, the chordamesoderm and neuroectoderm converge and extend under a genetic program.
  • This study investigates whether mechanical tension from these movements influences gene expression in these tissues.
  • By analyzing stretched midgastrula embryo explants, researchers found that mechanical stretching activates certain genes in the stretched trunk region while inhibiting others in low-stretch areas, suggesting that mechanical forces could regulate embryonic patterning and development.
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