Enhancing signal-to-noise ratio in real-time LED-based photoacoustic imaging: A comparative study of CNN-based deep learning architectures.

Recent advances in Light Emitting Diode (LED) technology have enabled a more affordable high frame rate photoacoustic imaging (PA) alternative to traditional laser-based PA systems that are costly and have slow pulse repetition rate. However, a major disadvantage with LEDs is the low energy outputs that do not produce high signal-to-noise ratio (SNR) PA images. There have been recent advancements in integrating deep learning methodologies aimed to address the challenge of improving SNR in LED-PA images, yet comprehensive evaluations across varied datasets and architectures are lacking.

In Vitro Engineered ECM-incorporated Hydrogels for Osteochondral Tissue Repair: A Cell-Free Approach.

Prevalence of osteoarthritis has been increasing in aging populations, which has necessitated the use of advanced biomedical treatments. These involve grafts or delivering drug molecules entrapped in scaffolds. However, such treatments often show suboptimal therapeutic effects due to poor half-life and off-target effects of drug molecules.

Microbial inheritance through seed: a clouded area needs to be enlightened.

Seed endophytes are actively used by the mother plant as both reservoir and vector of beneficial microbes. During seed dormancy endophytes experience significant physiochemical changes and only competent endophytes could colonise successfully in seeds and some of them act as obligate endophyte that are transmitted vertically across generations. The adaptive nature of endophytes allows them to switch lifestyles depending on environment and host conditions.

The Historical Case for a Strong and Diverse Neurology Clerkship Leadership Team.

The role of the clerkship director has evolved significantly over the past century and now requires a diverse range of skills to meet the rigorous standards set by national accrediting bodies such as the Liaison Committee on Medical Education. We conducted a historical exploration, spanning the past 43 years, of the educational practices in the Neurology Department at Johns Hopkins University School of Medicine. We learned that no entity is responsible for documenting the history of the clerkship.