Evaluation of the Articular Disc Using the Magnetic Resonance Cartigram in Asymptomatic and Symptomatic Temporomandibular Disorders.

 The study is aimed to perform magnetic resonance (MR) cartigram of the articular disc in patients with asymptomatic and symptomatic temporomandibular disorders (TMD).  Thirty-nine volunteers were divided into three groups: 16 symptomatic TMD, 16 asymptomatic TMD, and 7 controls. The articular disc was divided into three segments (anterior, middle, and posterior) and analyzed using morphological magnetic resonance imaging (MRI) and T2 mapping sequences.

Association of Demographic Disparities in Maternal Oral Hygiene Status, Caries Experience, and Oral Health Behavior Toward Children in Chengalpattu District, India: A Cross-Sectional Study.

Background And Objective:  Mothers are the primary caregivers throughout early childhood, playing a vital role in developing their child's oral health behavior, as oral conditions in primary teeth can have a considerable negative impact on the child's growth. This study aims to assess the association between maternal oral hygiene status, caries experience, and oral health behavior (OHB) toward their children.

Methodology: A cross-sectional study was conducted among 226 mothers of children aged nine months to three years visiting the primary health centers (PHCs) in urban (n = 113) and rural (n = 113) areas of Chengalpattu district, India.

Transit and Fairness: Exploring Spatial Equity in Accra's Public Transport System.

Globally, millions of individuals access services and opportunities on a daily basis using different modes of motorized and non-motorized transportation. However, in the global south, the role of public transport in providing access to services is relatively under-researched due to non-functional public transport services and poor infrastructure. This paper uses data from the Greater Accra Metropolitan Area (GAMA) to empirically contribute to the discourse on how public transport availability varies across different residential locations and assess if there is equitable access to Public Transport Infrastructure and Services (PTIS) across urban and peri-urban areas.

Antigen-specific T cell immunotherapy by in vivo mRNA delivery.

Immunotherapy has shown promise for treating patients with autoimmune diseases or cancer, yet treatment is associated with adverse effects associated with global activation or suppression of T cell immunity. Here, we developed antigen-presenting nanoparticles (APNs) to selectively engineer disease antigen (Ag)-specific T cells by mRNA delivery. APNs consist of a lipid nanoparticle core functionalized with peptide-major histocompatibility complexes (pMHCs), facilitating antigen-specific T cell transfection through cognate T cell receptor-mediated endocytosis.