Publications by authors named "A V Lukashin"
Their unique physicochemical properties and multi-enzymatic activity make CeO nanoparticles (CeO NPs) the most promising active component of the next generation of theranostic drugs. When doped with gadolinium ions, CeO NPs constitute a new type of contrast agent for magnetic resonance imaging, possessing improved biocatalytic properties and a high level of biocompatibility. The present study is focused on an in-depth analysis of the enzyme-like properties of gadolinium-doped CeO NPs (CeO:Gd NPs) and their antioxidant activity against superoxide anion radicals, hydrogen peroxide, and alkylperoxyl radicals.
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- Outer hair cells (OHCs) in the organ of Corti are crucial for converting mechanical sound signals into electrical responses and interact with inner hair cells (IHCs) through supportive cells, enhancing cochlear sensitivity and frequency selectivity.
- Researchers used a light-sensitive protein, halorhodopsin (HOP), to selectively activate supporting cells (Deiters' and outer pillar cells) in mice, observing changes in cochlear mechanics and IHC activity through measured electrical potentials.
- The study found that activating HOP in these supporting cells suppressed cochlear amplification and altered responses to sound, suggesting that targeting these cells could be a promising approach for treating noise-induced hearing loss.
Cochlear sensitivity, essential for communication and exploiting the acoustic environment, results from sensory-motor outer hair cells (OHCs) operating in a structural scaffold of supporting cells and extracellular cortilymph within the organ of Corti (OoC). Cochlear sensitivity control is hypothesized to involve interaction between the OHCs and OoC supporting cells (e.g.
View Article and Find Full Text PDFLiquid permeation and chemical stability of anodic alumina membranes.
Beilstein J Nanotechnol
March 2017
A study on the chemical stability of anodic alumina membranes and their performance in long-term water and organic solvent permeation experiments is reported. Anodic alumina possesses high stability for both protonic and aprotonic organic solvents. However, serious degradation of the membrane occurs in pure water, leading to a drastic decrease of permeance (over 20% of the initial value after the passing of 0.
View Article and Find Full Text PDFThe structural organization of compounds in a confined space of nanometer-scale cavities is of fundamental importance for understanding the basic principles for atomic structure design at the nanolevel. Here, we explore size-dependent structure relations between one-dimensional PbTe nanocrystals and carbon nanotube containers in the diameter range of 2.0-1.
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