[Involvement of rabbit motor cortex neurons in the instrumental behavior before and after chronic ethanol consumption: a comparison with the limbic cortex].

The effect of acute administration is significantly more prominent in the limbic (cingulate) than in the motor cortex [9]. We proposed that the limbic cortex is more sensitive also to chronic ethanol treatment (CET). It was shown that morphology as well as neuronal activity of the limbic cortex changed greatly after the CET [7].

A subset of cingulate cortical neurones is specifically activated during alcohol-acquisition behaviour.

Unlabelled: A new need is associated with the formation of behaviour directed at its satisfaction. In chronically ethanol-treated rabbits a bodily need develops to acquire and consume alcohol. The present study examined the firing properties of single neurones in the cingulate (limbic) cortex of chronically ethanol-treated rabbits.

Neuronal subserving of behavior before and after chronic ethanol treatment.

We have previously shown that an acute ethanol dose (1 g/kg), sufficient to impair the performance of a healthy rabbit, also reversibly depresses the activity of those limbic-cortex neurons that are specifically activated during recently learned behavioral acts. Our new morphological and neurophysiological data suggest a death of such neurons after 9-month chronic ethanol treatment. The effect of acute ethanol administration on neurons and performance speed in alcoholic rabbits was opposite to that found in healthy animals.

[Structural changes and reorganization of the activity of the cortical neurons in the behavior of chronically alcoholized rabbits].

Unit activity in the limbic cortex recorded during food acquisition behaviour was analyzed in the rabbits that were subjected to chronic (2.5-3.0 months) alcohol administration (CA).

Effect of ethanol on hippocampal neurons depends on their behavioural specialization.

Acute effect of ethanol on hippocampal neurons was studied during food acquisition behaviour in seven rabbits. The rabbits were taught to acquire food from a feeder by pressing a pedal on the same side of the cage. The behaviourally specialized units (L units related to newly learned behaviour and M units related to behaviour formed before learning, e.