Post-Chornobyl remote radiation effects on human sperm and seminal plasma characteristics.

Aim: The research was aimed on analysis of the remote consequences of Chornobyl accident on the reproductive function of men adult residing in Ukraine.

Materials And Methods: 232 male volunteers with mean age of 34 years (range 20-47) from 5 different regions of Ukraine (Zhytomyr, Ivano-Frankivsk, Kyiv, Poltava, and Kyiv city) were enrolled in cross-sectional studies of long term radiation effects on seminal plasma and sperm. All manipulations, analysis and classification of ejaculates were done accordingly to WHO recommendations.

[BIOMARKERS OF EARLY AND DIFFERENTIAL DIAGNOSIS OF PROSTATIC CANCER].

There were examined 87 patients, suffering prostatic gland diseases, in whom the level of general prostate-specific antigen (PSA) in the blood have constituted 0.5 – 30 ng/ml. In 27 of them prostatic gland diseases were not revealed, in 28 – prostatic cancer was diagnosed, and in 32 – benign prostatic hyperplasia.

Impact peculiarities of long-term gamma-irradiation with low-dose rate on the development of laboratory rats and their sperm production.

Objective: To study the influence of long-term gamma-irradiation with low dose rate (13×10-6 cGy/s) on the body, testes and ventral prostate, development of laboratory rats, as well as quantitative parameters of sperm production along with kinetic characteristics of spermatozoa.

Materials And Methods: The experiments were performed on laboratory white rats of 2,5 months in age. Animals were irradiated in gamma-field of "Ethalon" device in a dose range 0.

Analysis of the antioxidantive qualities of sperm after total body X-irradiation of animals.

To study dynamics of natural antioxidant levels and antioxidant enzymes activities in rabbit seminal fluid in conditions of single total body X-ray irradiation in different doses. Materials and methods. Soviet Shinshilla white rabbit males 30-36 months old were taken into investigation.

Variation of rabbit sperm physiologic parameters after the X-ray exposure.

Objective: To study the impact of X-irradiation on the morpho-functional characteristics of rabbit spermatozoa and the contents of fructose, L-carnitine, α-tocopherol, ascorbate and citrate in the animal sperm.

Materials And Methods: The total body irradiation of rabbits (Soviet Shinchilla) was performed at the RUM-17 device in the dose range of 1.0-7.