TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation.

Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive eye disease. GDLD is characterized by the loss of barrier function in corneal epithelial cells (CECs) and amyloid deposition due to pathogenic variants in the TACSTD2 gene. Limbal stem cell transplantation (LSCT) has been suggested as an effective therapeutic alternative for patients with GDLD.

Draft genome sequence of strain BH2, isolated from a pregnant leachate solution of heap bioleaching.

We report the draft genome sequence of a type strain Strain BH2, isolated from a pregnant leachate solution of industrial-scale chalcocite bioleach heap (Monywa, Myanmar). The genome is 1.7 Mbp long with a GC content of 34.

Draft Genome Sequence of Acidiplasma aeolicum Strain V1, Isolated from a Hydrothermal Pool.

We report the draft genome sequence of Acidiplasma aeolicum strain V1, isolated from a hydrothermal pool (Vulcano Island, Italy). The genome is 1.8 Mbp long with a GC content of 34%.

Identification of Clinically Significant Prostate Cancer by Combined and mRNA Detection in Urine Samples.

Purpose: Preclinical evaluation of and transcript simultaneous detection in urine to diagnose clinical significant prostate cancer (prostate cancer with Gleason score ≥7) in a Russian cohort.

Patients And Methods: We analyzed urine samples of patients with a total serum PSA ≥2 ng/mL: 31 men with prostate cancer scheduled for radical prostatectomy, 128 men scheduled for first diagnostic biopsy (prebiopsy cohort). , , and transcripts were detected by multiplex reverse transcription quantitative polymerase chain reaction, and the results were used for scores for calculation and statistical analysis.

Genome Sequences of a Green-Colored Chlorobium phaeovibrioides Strain Containing Two Plasmids and a Closely Related Plasmid-Free Brown-Colored Strain.

Here, we report the draft genome sequences of the green sulfur bacterium strains GrTcv12 and PhvTcv-s14, isolated from the chemocline zone from meromictic Lake Trekhtzvetnoe, separated from the White Sea, in Russia. This is the first report showing the presence of plasmids containing antiphage systems in the sp. genome.