Publications by authors named "A V Incognito"
Postural hyperventilation has been implicated as a cause of postural orthostatic tachycardia syndrome (POTS), yet the precise mechanisms underlying the heightened breathing response remain unclear. This study challenges current hypotheses by revealing that exaggerated peripheral chemoreceptor activity is not the primary driver of postural hyperventilation. Instead, significant contributions from reduced stroke volume and compromised brain perfusion during orthostatic stress were identified.
View Article and Find Full Text PDF: Although different hypotheses have been proposed over time, there is a dearth of information on factors able to predict the response to treatment for idiopathic sudden sensorineural hearing loss (ISSNHL) and hearing recovery. The aim of this study was to apply univariate and multivariate statistical models in a retrospective clinical setting of patients given therapy for ISSNHL at our tertiary academic audiological centers to investigate the prognostic value of clinical signs, symptoms, and comorbidities in relation to hearing recovery. : The inclusion criteria were: history of ISSNHL diagnosed and treated at the Padova or Modena tertiary academic audiological centers; age ≥ 18 years; availability of clinical and audiological outcome data.
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- * A study in Northeastern Italy analyzed 57 patients with GJB2/GJB6 mutations and categorized them by mutation types, revealing 59.64% had homozygous mutations and distinct hearing thresholds based on genotype.
- * The findings suggest further research is needed to deepen understanding of the clinical and audiological characteristics tied to GJB2/GJB6 mutations, indicating that larger studies are essential for broader confirmation.