[Efficacy and tolerability of pantogam activ in patients with partial epilepsy].

Randomized double-blind, placebo-controlled study to determine efficacy and tolerability of pantogam activ as an add-on drug in patients with partial epilepsy was conducted. 20 patients received pantogam activ, 20 patients - placebo. Good tolerability and no advers event were detected in the dose of 1800 mg/d.

[Lyrica (pregabalin) in the treatment of focal refractory epilepsy in adults].

Efficacy and tolerability of a new antiepileptic drug pregabalin (lyrica) as an add-on drug in patients with focal refractory epilepsy was analyzed. The most commonly used dosage was 450 mg/d. For the 6-month treatment of 19 patients, aged 18-30 years, a positive effect of the combined therapy was observed in 68,4%, the remission was achieved in 31,6% and the significant improvement in 36,8%.

[Use of computer technologies in prosthetic treatment of patients with front teeth loss].

Use of the proposed computer modeling technology with taking into account the individual face size based upon multivariate statistical analysis with the possibility of art editing during the final stage of modeling let to take into consideration individual peculiarities of face structure and gender differences and to recreate individual form and sizes of front artificial teeth for non removable prosthetics. The results of computer modeling use in prosthetic treatment of patients with front teeth loss and the results of comparison with traditional method and also with preliminary use of computer modeling were demonstrated.

[Epilepsy and pregnancy].

Course and outcome of 200 pregnancies, deliveries and post-partum periods of 127 women with the onset of epilepsy before or during pregnancy were compared to clinical form of the disease, frequency of seizures and antiepileptic therapy. In addition, 104 children born to 97 mothers with epilepsy, 85 children--from the moment of birth to 1 year old and others from 1 to 16 years old, were studied. The particular attention was focused on the early neonatal adaptation.