Publications by authors named "A V Holst"
This review summarises the current knowledge of posterior reversible encephalopathy syndrome which is an acute and severe neurological condition characterised by headache, encephalopathy, epileptic seizures, and visual disturbances. Typical radiological findings are cerebral vasogenic oedema, predominantly localised in the posterior cerebral circulation. The exact pathophysiological mechanisms remain unknown but involve dysfunction of the blood-brain barrier.
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- The study aimed to assess the survival and clinical quality of individually layered indirect composite restorations (ICRs) in patients aged 6 to 50 across two locations, focusing on outcomes from 2008 to 2018.
- A total of 155 restorations were evaluated, revealing high success rates of 95.4% at 1 year, 87.4% at 5 years, and 78.8% at 10 years, with over 90% rated as excellent or good in clinical quality.
- While the restorations demonstrated strong success, restored teeth had more plaque buildup compared to unrestored teeth, indicating a notable difference in periodontal health.
DNA transfer is ubiquitous in the human gut microbiota, especially among species of the order Bacteroidales. In silico analyses have revealed hundreds of mobile genetic elements shared between these species, yet little is known about the phenotypes they encode, their effects on fitness, or pleiotropic consequences for the recipient's genome. In this work, we show that acquisition of a ubiquitous integrative conjugative element (ICE) encoding a type VI secretion system (T6SS) shuts down the native T6SS of .
View Article and Find Full Text PDFPurpose: Hydrocephalus presents diagnostic and management challenges due to its heterogeneity. The ASPECT Hydrocephalus System, introduced in 2023, offers a comprehensive approach to describing patients with hydrocephalus. This study investigates the clinical applicability of the ASPECT Hydrocephalus System compared to the International Classification of Disease (ICD-10) and demonstrates its utility.
View Article and Find Full Text PDFIntroduction: Clinical reasoning in veterinary medicine is often based on clinicians' personal experience in combination with information derived from publications describing cohorts of patients. Studies on the use of scientific methods for patient individual decision making are largely lacking. This applies to the prediction of the individual underlying pathology in seizuring dogs as well.
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