Efficacy and Safety of Altibrain® as an Adjunctive Therapy for Autism Spectrum Disorder: An Open Label Trial Targeting Core Symptoms.

Objective: This study aimed to evaluate the effectiveness and safety of Altibrain® in combination with standard Autism Spectrum Disorder (ASD) treatment compared to standard ASD treatment alone in individuals diagnosed with ASD.

Method: A randomized, open-label trial was conducted involving 120 participants aged 3 to 17 years, randomly assigned to either the Standard ASD Treatment group or the Altibrain® + Standard ASD Treatment group. Sixty patients were randomly allocated to each Standard ASD Treatment group or the Altibrain® + Standard ASD Treatment group.

Methylenetetrahydrofolate Reductase Gene Polymorphism as a Risk Factor for Coronary Artery Disease.

Hyperhomocysteinemia (HHcy) is one of the factors contributing to the pathogenesis of coronary artery disease (CAD). Besides nutritional deficiency disorders, genetic polymorphism predominantly related to point mutation in the gene coding for Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in the metabolism methionine-homocysteine (Hcy) has been implicated in HHcy. PubMed survey related to MTHFR gene polymorphism in CAD retrieved 143 articles from which 20 were selected in which MTHFR gene polymorphism and Hcy were estimated.

Numerical and experimental methods for the assessment of a human finger-inspired soft pneumatic actuator for gripping applications.

The increasing demand for soft robotic systems in agricultural, biomedical and other applications has driven the development of actuators that can mimic the flexibility and adaptability of human muscles. Several studies have explored the design and implementation of soft actuators for robotic applications, however, there is a need for soft actuators demonstrating delicate gripping capabilities but also excel in specific biomedical applications, such as therapeutic massaging. The objective of this work is to develop a multi-finger soft pneumatic actuator mimicking human fingers for Ayurvedic therapeutic massaging and gripping applications.

The Role of Different Modalities of Regenerative Therapies in the Treatment of Erectile Dysfunction: A Global Survey and Global Andrology Forum Expert Recommendations.

Purpose: There is increased interest in regenerative therapies (RTs) to treat erectile dysfunction (ED). However, the need for society's guidelines has led to varied practices. This study aims to investigate current global practices, address the heterogeneity in treatment protocols and evaluations, and establish expert recommendations in clinical practice.

Leveraging SERS and Transformer Models for Simultaneous Detection of Multiple Pesticides in Fresh Produce.

The widespread use of pesticides in agriculture poses food safety and environmental risks, highlighting the need for rapid detection techniques to mitigate contamination. Surface-enhanced Raman spectroscopy (SERS) coupled with machine learning provides a powerful approach for the detection and quantification of multiple pesticides in agricultural products. This study introduces the SERSFormer-2.