Associations of Toll-like Receptor Gene Polymorphisms with NETosis Activity as Prognostic Criteria for the Severity of Pneumonia.

Unlabelled: was to determine the molecular genetic prognostic criteria for the severity of the course pneumonia based on the analysis of the association of genetic polymorphism in toll-like receptors with the severity of NETosis.

Materials And Methods: The study included 38 patients with the main diagnosis of community-acquired pneumonia with a severe course. All the patients underwent standard clinical laboratory examinations, computed tomography of the thoracic organs, microbiological examination of blood and tracheobronchial aspirate.

Controlling and Fine-Tuning Charge-Transfer Emission in 2,6-Dicyanoaniline Multichromophores Prepared through Domino Reactions: Entry to a Potentially New Class of OLEDs.

Substituted 2,6-dicyanoanilines are versatile electron donor-acceptor compounds, which have recently received considerable attention, since they exhibit strong fluorescence and may have utility in the synthesis of fluorescent materials, non-natural photosynthetic systems, and materials with nonlinear optical properties. The majority of known synthetic procedures are, however, "stop-and-go" reaction processes involving time-consuming and waste-producing isolation and purification of product intermediates. Here, we present the synthesis of substituted 2,6-dicyanoanilines via atom-economical and eco-friendly one-pot processes, involving metal-free domino reactions, and their subsequent photochemical and photophysical measurements and theoretical calculations.

[The prevalence of diseases of non-occupational genesis in persons with diagnosis of occupational disease].

The data on prevalence of diseases of non-occupational genesis in persons with occupational diseases that have stopped their labor activity are presented. The purpose of the study was to analyze prevalence of diseases of non-occupational genesis in persons with diagnose of occupational disease working at enterprises and organizations served by health care institutions of the FMBA of Russia. The study uses data from "The Industrial Register of persons with occupational diseases".

Comparative In Vitro Evaluation of Antibacterial and Osteogenic Activity of Polysaccharide and Flavonoid Fractions Isolated from the leaves of .

The osteogenic, cytotoxic, and antibacterial activities of polysaccharide (PS-SC) and flavonoid (F-SC) fractions isolated from the leaves extract of were studied in vitro. F-SC consists of the five quercetin glycosides in the ratio 2:8:10:1:4, which were isolated from the leaves extract of and have been characterized previously. PS-SC was first isolated from the leaves extract of and has been described.

Chelidonic Acid and Its Derivatives from : Isolation, Structural Elucidation and Influence on the Osteogenic Differentiation of Multipotent Mesenchymal Stromal Cells In Vitro.

4-oxo-4-pyran-2.6-dicarboxylic acid (chelidonic acid, ChA) in the native state and in the complex with calcium [Ca(ChA)(HO)], named saucalchelin (CaChA), was isolated from the extract of leaves for the first time for the family. The structure of ChA was determined by NMR, MS and confirmed by X-ray analysis of its monomethyl ester, and CaChA was described by IR, ICP-MS, CHN analysis.