[The activity of the first line enzymes of the antioxidant defence in the liver of pubertal rats during stress].

The purpose of the work was to study the activity of the first line antioxidant defence enzymes in postmitochondrial fraction of liver of pubertal rats during immobilization stress. During short-term immobilization the activity of catalase and glutathione peroxidase (GPx) decreased. Long-term immobilization was accompanied by activation of GPx and superoxide dismutase in the liver postmitochondrial fraction of late pubertal and adult animals, but not early pubertal rats.

[Age-related peculiarities of glutathione content changes in the brain of rats during immobilization stress].

The work is aimed at studying age-related peculiarities as regards glutathione content changes in the brain of rats under immobilization stress. It has been established that some changes in the content of reduced glutathione take place in the brain in the process of ontogenesis. During immobilization stress the content of this metabolite decreases in the brain of all age groups of rats under study.

[Androgenic function of the adrenal cortex in girl athletes with retarded sexual development].

Diurnal excretion of 17-ketosteroids and their fractions was studied in 43 girl athletes with retarded sexual development (RSD) and 22 patients who did not go in for sports. Twenty-five healthy girls with a normal menstrual cycle constituted the control group. Athletes with RSD showed relative hyperandrogeny marked by a higher proportion of more active androgenic fractions (dehydroepiandrosterone and androsterone) in total 17-ketosteroids.