Publications by authors named "A V Florschutz"

Case: A 69-year-old woman presented with a type IIIB left proximal humerus fracture with a 500-square-centimeter soft tissue defect, 10-cm bone defect, and radial nerve laceration after a tiger attack. The surgical intervention included proximal humeral replacement with muscular integration, radial nerve repair, and latissimus dorsi flap coverage.

Conclusion: This case presents an exceedingly rare injury mechanism resulting in a significant soft tissue and bone defect.

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Article Synopsis
  • - A clinical trial compared intensive treatment strategies for non-M3 AML in patients aged 60 and over against a standard treatment known as CSA, involving a total of 1,286 participants.
  • - The study found that rates of complete remission at 90 days and five-year event-free survival were similar across CSA and the other intensive treatment groups, with no significant differences observed.
  • - Overall, the more intensive treatment strategies did not lead to better outcomes in terms of event-free survival or overall survival compared to the standard CSA treatment based on the evaluated data.
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Background: Cancer regularly disrupts health and developmental trajectories in adolescents and young adults (AYAs). Parents have been shown to have a substantial impact on the health and cancer survivorship activities of AYA patients in the form of symptom management. However, no randomized controlled trial has evaluated a coping support intervention (CSI) program for parents of AYAs with cancer aged 18 to 40 years.

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  • A clinical trial tested two new drug combinations for treating relapsed/refractory B-cell non-Hodgkin lymphoma, focusing on patients with follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL).
  • Results showed that complete response rates were modest, with FL patients achieving up to 33% and DLBCL patients achieving 13% at the end of induction treatment.
  • Despite these response rates, significant safety concerns were identified, leading to the decision not to pursue further development of the studied combinations.
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