Publications by authors named "A V Epifantsev"

Article Synopsis
  • The study examines how juvenile Baikal whitefish, both preadapted and non-adapted, respond at the genetic level to heat shock after being exposed to temperature changes during their development.
  • Preadapted fish experienced a controlled thermal rise during their growth, while both groups were tested under standard and increased temperature conditions to measure gene expression responses.
  • The findings show that preadapted fish had heightened expression in genes related to immune response and growth, while non-adapted fish showed increased activity in metabolism-related genes, highlighting differences in how these two groups handle thermal stress.
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Article Synopsis
  • Acclimation through the hormesis effect enhances flexibility in organisms, which has been confirmed in various ectothermic species, including the Baikal whitefish, by examining telomere length and gene expression.
  • The study found that while acclimation and acute temperature stress did not affect telomere length, they did influence telomerase activity, with acclimated larvae showing decreased activity and stressed larvae showing increased activity.
  • Acclimated larvae exhibited increased expression of genes involved in antioxidant defense, indicating a better ability to manage oxidative stress compared to non-acclimated larvae, along with changes in telomere-related gene expression under stress.
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The aim of this study was to improve results of treatment of patients with degenerative disc disease at the long-term period after microdiscectomy by developing unique algorithm for diagnosis and treatment of persisting pain syndrome. Patients were divided into two groups. First one included 198 patients with reflex-pain syndromes.

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The article presents analyze of results of treatment of 3 patients with initial caseous osteitis and of 49 patients with progressing spondylitis. Stabilizing operations on the axis were effectuated with using of dynamic constructions for back stabilization of axis, autotransplants and cellular implants in conditions of frontal spondylosyndesis. There were achieved good results of treatment of ventral spondylosyndesis by autotransplants in 76.

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