Immune System and Regeneration.

The review article is devoted to a role of pluripotent stem cells and immune system in renewal of tissues (regeneration). Cell-precursors (progenitor cells) and differentiated cells can be divided a limited number of times and aren't capable of ensuring regeneration of tissues during the whole process of ontogenesis. The renewal of tissues during the whole long period is impossible without the participation of a specialized system which is responsible for regeneration.

[Early reactive changes of the astrocytes in the midbrain paranigral nucleus after forebrain ischemia and cerebroprotector Ropren administration in rats].

The aim of this study was to detect morphological equivalents of cerebroprotective effect of polyprenol drug Ropren on the astrocytes of the midbrain paranigral nucleus (PNN) which are located outside the focus of forebrain ischemia in rats. In mature rats (n = 8) the cerebral ischemia was reproduced under the narcosis by bilateral occlusion of both carotid arteries. Four rats received daily intraperitoneal injections of 11.

[On the method of forensic medical examination of the injuries inflicted and traces left by the objects having the rubber surface].

A method of forensic medical examination of the injuries inflicted and traces left by the objects having the rubber surface is proposed. The method permits to reveal the facts of contact of injurious rubber things with biological and non-biological objects. Its application extends the possibilities for determining the direction of movement and the weight of a vehicle running over the body of the victim.

[Reactive changes of the rat brain cellular elements under different conditions of circulatory hypoxia].

The aim of this study was to detect structural, spatial and quantitative changes of cellular elements of midbrain paranigral nucleus (PNN) and telencephalic anterior cingulate area (ACA) under different conditions of circulatory hypoxia. PNN anteriormedial part and ACA layers V-VI were examined in adult rats 7 days (n=4) after an occlusion of both common carotid arteries as well as in intact (1st control, n=4) and sham-operated animals (2nd control, n=4). In histological the sections, stained with Nissl cresyl violet, and using the methods of glial fibrillary acidic protein and an Ibal-protein detection, the proportions of unmodified, hypochromic, pyknomorphic neurons and ghost cells were determined as well as the numbers of astrocytes, oligodendrocytes, microgliocytes and endotheliocytes.

[Structure of venular vessels and cellular composition of hepatic sinusoidal capillaries in newborn infants].

The objective of this study was to identify the structural peculiarities of terminal interlobular venules and to determine the number of endotheliocytes, hepatic fat-storing cells (FSC) and stellate macrophages (SM) in the liver of newborn infants. Liver fragments were obtained from 5 healthy newborn infants during medico-legal autopsies. In the sections stained using Mallory's method, the relation of the connective tissue of terminal portal tracts with the adventitia of interlobular veins was determined.