[Contribution of irreversible morphological changes of different renal structures to development of anemia in immune glomerulopathies].

Aim: To find out correlations between severity of sclerotic affection of the glomeruli, tubules, interstitium, vessels and development of anemia in patients with glomerulopathy.

Material And Methods: Assay of global and segmentary sclerosis, semiquantitative morphometry of severity of atrophic tubular changes, diffuse interstitial fibrosis, vascular changes (arteriolohyalinosis, elastofibrosis and perivascular sclerosis) were made in parallel with analysis of clinical laboratory data in 276 cases of chronic primary glomerulopathy with morphologically verified diagnosis by vital renal biopsy.

Results: Hemoglobin concentration and advance of anemia correlate negatively with severity of diffuse interstitial fibrosis and atrophic tubular alterations.