[The immune status in different clinical forms of insulin-dependent diabetes mellitus].

Immune status with reference to the disease duration and genetic factors (HLA-typing) was studied in various clinical variants of insulin-dependent diabetes mellitus. The disease duration appeared the key factor in development of immune deficiency in insulin-dependent diabetes mellitus. Critical immunological values were established (CD5+ cells--1200 in 1 microliter, CD4+ cells--35%, expression of CD5 and antigens HLA class II--110 and 75%, respectively) for septic complications which are highly probable in lower indices.

[Current problems of nuclear medicine in immunology].

The authors describe in a systemic order the potentialities of the use of nuclear medicine methods in immunology. Two fields of their application were singled out: experimental and clinical immunology, each one including in vivo and in vitro methods. The authors cited examples of their use, emphasizing the importance and prospects of radioimmunoassays for determination of the level of hormones in patients with various immunological pathology.

[Clinical aspects of the radioimmunoassay of carcinoembryonic antigen levels in breast cancer].

The paper is concerned with the results of radioimmunoassay of the CEA level in the blood serum of 235 patients with breast cancer, 48 patients with fibrous-cystic mastopathies and 51 healthy women. In 100 patients with generalized breast cancer repeated examination of the CEA level was done during drug treatment. The authors showed a possibility to use in practice the results of radioimmunoassay of CEA in patients with breast cancer in early stages as a prognostic test as well as an additional criterion in the evaluation of drug therapeutic efficacy in patients with generalized breast cancer.