Publications by authors named "A V Bacca"

Article Synopsis
  • - Renal denervation (RDN) is a safe and effective treatment option for hard-to-treat hypertension, showing blood pressure reductions similar to many common antihypertensive medications.
  • - RDN is best considered alongside lifestyle changes and traditional medical therapies, highlighting the importance of a comprehensive approach to manage hypertension effectively.
  • - Ongoing research is essential to understand RDN's impact on overall health outcomes and to pinpoint which patients are most likely to benefit from the procedure.
View Article and Find Full Text PDF

Arterial hypertension is the most prevalent cardiovascular risk factor worldwide. Despite the availability of many and effective antihypertensive medications, the prevalence of uncontrolled blood pressure (BP) remains high. As sympathetic hyperactivity has long been recognized as a major contributor to resistant hypertension, catheter-based renal denervation (RDN) has emerged as a new strategy to reduce BP.

View Article and Find Full Text PDF
Article Synopsis
  • The case study discusses a rare adrenal neoplasm misidentified as pheochromocytoma but found to be an adrenal cortical tumor upon histological examination.
  • The diagnosis was supported by electron microscopy, which showed neuroendocrine granules alongside lipid droplets in the tumor cells.
  • Following laparoscopic surgery to remove the tumor, the patient's urine levels of metanephrine and normetanephrine returned to normal, highlighting the importance of accurate diagnosis when symptoms and lab results differ from histological findings.
View Article and Find Full Text PDF

Aims: We explored multiple cardiometabolic patterns, including inflammatory and congestive pathways, in patients with heart failure (HF).

Methods And Results: We enrolled 270 HF patients with reduced (<50%, HFrEF; = 96) and preserved (≥50%, HFpEF; = 174) ejection fraction. In HFpEF, glycated hemoglobin (Hb1Ac) seemed to be relevant in its relationship with inflammation as Hb1Ac positively correlated with high-sensitivity C-reactive protein (hs-CRP; Spearman's rank correlation coefficient ρ = 0.

View Article and Find Full Text PDF

Congenital hypothyroidism (CH) may be caused by biallelic variants in the TSHR gene. CH due to thyroid dysgenesis has also been linked to pathogenic variants of the nucleotide kinase 2, homeobox 5 (NKX2-5) gene, which can also cause sudden cardiac death from ventricular arrhythmia. In particular, the NKX2-5 p.

View Article and Find Full Text PDF