[Studying the role of FASCIATA5 gene in the regulation of flower development in Arabidopsis thaliana].

Identification of new genes involved in the control of flower initiation and development, is an important problem of the plant developmental genetics. Central approach to solve it is the study of mutants with changes in these characters. The effect of pleiotropic mutation fasciata5 on the transition to the reproductive stage and flower development was studied.

[Pleiotropic effect of the fas5 mutation on the shoot development of Arabidopsis thaliana].

The paper described a new mutation that causes the development of multiple meristematic foci as part of shoot apical meristem, which can give rise to new stem axes or cause stem fasciation. The wus-1 mutation represses development of additional apical meristem in fas5 mutant, indicating to the sequential action of the genes in the formation of the shoot apical meristem and FAS5 gene participation in spatial restriction of the WUS gene expression. This function gene FAS5 performs independently of other negative regulators of WUS gene--namely genes CLV, as demonstrated by additive phenotype of double mutants fas5 clv2-1 and fas5 clv3-2.

[The gene NANA regulates cell proliferation in Arabidopsis thaliana shoot apical meristem without interaction with CLV1, CLV2, CLV3].

A constancycy of stem cell pool in shoot apical meristem of Arabidopsis thaliana is provided by a genetic regulation system with negative feedback loop based on the interaction of the gene WUS, which maintains indeterminate state of cells, with CLV genes, which restrict the level of WUS expression and stem cell pool size. clv mutations lead to an increase in the pool of stem cells in the apical and floral meristems and wus mutation leads to the opposite effect. Mutation na (nana), like wus mutation, causes premature termination of shoot apical meristem function, although it does not affect the activity of the flower meristem.

[Asymmetries in the serum ceruloplasmin concentration of patients with spondylogenic lumbosacral radiculitis].

The levels of ceruloplasmin in the serum of blood taken from the veins of the back side of the foot were determined in 66 patients with the radicular syndrome of lumbar osteochondritis and in 7 normal subjects (control). In the patients, the level of ceruloplasmin was significantly elevated, especially on the side of the pain syndrome and, hence, Lasegue's sign was also more pronounced. In patients without pain lateralization, an increase in ceruloplasmin levels was symmetrical.