Publications by authors named "A Utrera"

Aim: Gastric emptying scintigraphy is used to assess patients with symptoms of dyspepsia or gastroparesis. An alteration of fundus accommodation may explain these symptoms. The aim of this study was to determine the accommodation in gastric emptying scintigraphy studies performed in our institution.

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Gestation under chronic hypoxia causes pulmonary hypertension, cardiovascular remodeling, and increased aortic stiffness in the offspring. To mitigate the neonatal cardiovascular risk, pharmacological treatments (such as hemin and sildenafil) have been proposed to improve pulmonary vasodilation. However, little is known about the effects of these treatments on the aorta.

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  • The Constrained Mixture Model (CMM) offers a new way to analyze how arterial walls behave by considering them as a mix of different materials with specific properties and adjustments in their stretched state.
  • While some studies have shown the model's effectiveness, there is a lack of experimental methods tailored for patient-specific conditions.
  • The proposed solution involves a numerical-experimental fitting procedure to fine-tune material parameters and stretch values, successfully calibrating the model with experimental data from the descending thoracic aorta and showing a consistent relationship between stretches and strain measurements.
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This work consists of analyzing the impact of geometrical features (thickness and curvature) on the estimation of circumferential residual stresses in arteries. For this purpose, a specific sample of lamb abdominal artery is chosen for analysis and, through computational tools based on Python libraries, the stress-free geometry is captured after the ring opening test. Numerical simulations are then used to reconstruct the sample in order to estimate the circumferential residual stresses.

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  • Bone implants and replacements face challenges due to limited donor availability and high rejection rates, prompting the use of tissue engineering strategies to create new solutions.
  • This research focused on developing a cellular scaffold with a complex internal structure using 3D printing and salt leaching, along with a biocompatible hydrogel film that formed wrinkled micropatterns to enhance contact area and biocompatibility.
  • The study found that while adding nano-hydroxyapatite particles slightly affected the material's mechanical strength, it didn't significantly boost cell viability; however, the combination of the hydrogel and porous structure improved cell viability compared to untreated samples.
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