The Association of Spousal Relationship Quality and Social Support With Maternal-Infant Bonding: Moderating Roles of Maternal Age and Paternal Occupation.

This study examined associations between spousal relationship quality and social support with mother-infant bonding among women in Rawalpindi, Pakistan (Intervention Arm: n = 352, M = 25.1, SD = 4.7; Control Arm: n = 358, M = 25.

Developing a tool to evaluate the impact of a student-led community-engaging health promotion project on knowledge translation skills in medical students.

Background: Medical student-led health promotion projects are pivotal in enhancing community health and medical education. However, research focusing on the impact of such projects on medical students' knowledge translation skills is limited. This study aims to address this gap by developing and validating a survey tool to assess the knowledge translation skills and overall impact of a student-led health promotion project.

Parent and Primary Care Clinician Perceptions About Pediatric Hypertension.

Importance: Despite published guidelines and a prevalence of pediatric hypertension of approximately 3%, less than 25% of affected children are identified, with 60% not receiving any intervention despite detection. Understanding the knowledge and perceptions of parents or caregivers and health care teams is crucial to identify factors that may contribute to these unacceptably low detection rates.

Objective: To examine the knowledge and perceptions of parents and health care teams regarding pediatric hypertension to identify common themes contributing to low hypertension detection.

Safety and efficacy of mitapivat in sickle cell disease (RISE UP): results from the phase 2 portion of a global, double-blind, randomised, placebo-controlled trial.

Background: Sickle cell disease, a debilitating, inherited haemolytic anaemia with premature morbidity and mortality, affects millions globally. Mitapivat, a first-in-class, oral, allosteric activator of pyruvate kinase, improves red blood cell survival by increasing ATP and diminishes sickling by decreasing 2,3-diphosphoglycerate. We aimed to evaluate the efficacy and safety of mitapivat in patients with sickle cell disease.