Publications by authors named "A U Bing"
Evolution of dupilumab-associated conjunctivitis in patients with atopic dermatitis after switching dupilumab to tralokinumab or Janus kinase inhibitors (RESO-ADOC study).
J Eur Acad Dermatol Venereol
November 2024
Background: Clinical trials and real-life data have reported an increased incidence of conjunctivitis in patients treated with dupilumab for their atopic dermatitis (AD). Although mostly mild in severity, in some cases conjunctivitis will appear or increase after dupilumab initiation, which can lead to dupilumab discontinuation.
Objectives: (1) To describe the characteristics of patients developing conjunctivitis requiring discontinuation of dupilumab; and (2) to analyse the factors associated with a complete conjunctivitis improvement after dupilumab discontinuation and a switch to tralokinumab or Janus kinase inhibitors.
Article Synopsis
- Patients with end-stage ankle osteoarthritis face limited mobility and have two main surgical options: total ankle replacement (TAR) and ankle fusion (AF).
- The study aimed to compare the costs and quality of life improvements associated with TAR versus AF over 52 weeks and over the patients' lifetime, using a cost-utility analysis on 282 participants from a trial.
- Results showed TAR was more expensive than AF at 52 weeks, with a cost-effectiveness ratio indicating TAR isn't cost-effective in the short term; however, long-term modeling suggested it could become cost-effective, with a 69% likelihood if using a threshold of £20,000 per quality-adjusted life-year gained.
Introduction: Entering an animal shelter is a stressful experience for dogs that can impair their welfare, adoptability, and shelter staff safety; thus, it is crucial to reduce the stress experienced during intake. This study investigated the current intake practices for dogs admitted in animal shelters in Texas, United States.
Methods: To gather data, an online survey was designed and distributed to shelter employees responsible for intake at animal shelters.
Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
View Article and Find Full Text PDFBackground: End-stage ankle osteoarthritis causes severe pain and disability. There are no randomized trials comparing the 2 main surgical treatments: total ankle replacement (TAR) and ankle fusion (AF).
Objective: To determine which treatment is superior in terms of clinical scores and adverse events.